An inflammatory marker for predicting prostate cancer in prostate biopsy: monocyte-to-lymphocyte ratio

Objective: To evaluate the predictive role of inflammatory parameters, especially monocyte-to-lymphocyte (MLR) ratio, on diagnosis prostate cancer (PCa). Material and Methods: The data patients undergoing biopsy between July 2015 2019 were retrospectively analyzed. including age, PSA, neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), MLR histopathologies recorded. Patients grouped as benign prostatic hyperplasia (BPH), PCa prostatitis according to PBx histopathology all variables Results: Pathology results 338 are follows: 124 (36.7%) BPH, 132 (39.1%) 82 (24.3%) prostatitis. with older had higher serum PLR, NLR values compared non-PCa patients. In comparison made by excluding metastatic patients, only PSA remained statistically high. All three parameters significant AUC predict in entire-cohort, but cohort which excluded. Multivariate logistic regression analysis revealed that independent predictors PCa. Conclusion: our study, it was observed among markers found be high continued nonmetastatic multivariate model created from MLR, a predictor like PSA. can used an inexpensive, easily accessible applicable new marker Keywords: markers, biopsy,